Significance of downregulation of renal organic cation transporter (SLC47A1) in cisplatin-induced proximal tubular injury [Corrigendum]
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[This corrects the article on p. 1701 in vol. 8, PMID: 26203260.].
منابع مشابه
Significance of downregulation of renal organic cation transporter (SLC47A1) in cisplatin-induced proximal tubular injury
BACKGROUND/AIM To elucidate the mechanism responsible for developing acute kidney injury in patients with diabetes mellitus, we also evaluated the issue of whether advanced glycation endproducts (AGEs) influence the expressions of multi antimicrobial extrusion protein (MATE1/SLC47A1) in tubular cells. MATERIALS AND METHODS To detect changing expression of MATE1/SLC47A1 in dose- and time-depen...
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The usefulness and efficacy of cisplatin, a chemotherapeutic drug, are limited by its toxicity to normal tissues and organs, including the kidneys. The uptake of cisplatin in renal tubular cells is high, leading to cisplatin accumulation and tubular cell injury and death, culminating in acute renal failure. While extensive investigations have been focused on the signaling pathways of cisplatin ...
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